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Table 1 Demographic and clinical characteristic of the RA patients

From: CTLA4-Ig treatment induces M1–M2 shift in cultured monocyte-derived macrophages from healthy subjects and rheumatoid arthritis patients

Demographic characteristics of the RA patients

 Age (years, mean ± SD)

54 ± 13

 Sex (female/male)

4/1

Autoantibodies and RA patients with hand RX erosions

 +RF (n/5 = %)

3 (60%)

 +ACPA (n/5 = %)

3 (60%)

 Rx erosions (n/5 = %)

3 (60%)

Disease duration (years, mean ± SD)

6.4 ± 5

 0–5 years (n/5 = %)

3 (60%)

 5–10 years (n/5 = %)

2 (40%)

 > 20 years (n = %)

0 (0%)

Comorbidities

 Hypertension (n/5 = %)

3 (60%)

 Diabetes (n = %)

0 (0%)

 Anaemia (n = %)

0 (0%)

 Sjogren’s syndrome (n = %)

0 (0%)

 Heart failure (n = %)

0 (0%)

 Acute cardiac ischemic (ACI) (n = %)

0 (0%)

 Allergic asthma (n = %)

0 (0%)

 Dyslipidaemia (n/5 = %)

1 (20%)

 Neoplasia (n = %)

0 (0%)

 Osteoporosis (n/5 = %)

3 (60%)

 Dysthyroid (n/5 = %)

1 (20%)

H. pylori (n = %)

0 (0%)

 HBV (n = %)

0 (0%)

NSAID treatment

 NSAIDs (n/5 = %)

1(20%)

Glucocorticoid treatment

 Prednisone (n/5 = %)

1 (20%)

 Modified release prednisone (n/5 = %)

2 (40%)

csDMARD treatment

 Methotrexate (n/5 = %)

3 (60%)

 Leflunomide (20 mg/day) (n/5 = %)

2 (30%)

bDMARD treatment

 TNF inhibitors (n/5 = %)

1 (20%)

 Abatacept (n = %)

0 (0%)

 Rituximab (n = %)

0 (0%)

 Tocilizumab (n = %)

0 (0%)

Other treatments

 Vitamin D (n/5 = %)

4 (80%)

 Folic acid supplementation (5 mg/week) (n/5 = %)

3 (60%)

Clinical score and laboratory findings

 Tj (mean ± SD)

5 ± 2.97

 Sj (mean ± SD)

1.8 ± 1.47

 VAS (mean ± SD)

5.2 ± 2.63

 CRP (mg/dL, mean ± SD)

11.36 ± 16.47

 DAS (CRP) (mean ± SD)

3.71 ± 0.56

  1. SD standard deviation, RF rheumatoid factor, ACPA anticitrullinated protein antibodies, H. pylori Helicobacter pylori, HBV hepatitis B virus, NSAIDs nonsteroidal anti-inflammatory drug, MR prednisone modified release prednisone, csDMARDs conventional synthetic disease-modifying anti-rheumatic drugs, bDMARDs biological disease-modifying anti-rheumatic drugs, TNF inhibitors tumor necrosis factor inhibitors, TJ tender joints, SJ swollen joints, VAS visual analogue scale, CRP c-reactive protein, DAS disease activity score