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Table 3 Risk factors of hematological malignancies development in SLE patients

From: Hematological malignancies in systemic lupus erythematosus: clinical characteristics, risk factors, and prognosis—a case-control study

Parameter

Univariate logistic analysis

Multivariate logistic analysis

OR(95% CI)

P value

OR(95% CI)

P value

Age at SLE diagnosis

1.075 (1.028–1.125)

0.002*

1.122 (1.037–1.214)

0.004*

Infection

5.077 (1.523–16.925)

0.008*

4.289 (0.598–30.768)

0.148

Splenomegaly

4.667 (1.351–16.115)

0.015*

2.051 (0.177–23.739)

0.565

Hemoglobin

0.970 (0.945–0.998)

0.038*

0.959 (0.918–1.001)

0.055

TC

0.499 (0.244–1.022)

0.057

-

-

HDL

0.029 (0.002–0.359)

0.006*

0.039 (0.001–1.383)

0.075

CRP

1.011 (0.990–1.033)

0.320

-

-

Anti-dsDNA antibody

0.182 (0.051–0.647)

0.009*

0.238 (0.035–1.636)

0.145

SLEDAI-2K at SLE diagnosis

0.952 (0.873–1.038)

0.264

-

-

  1. *Statistical significance (P<0.05)
  2. Abbreviations: SLE, systemic lupus erythematosus; TC, total cholesterol; HDL, high-density lipoprotein; CRP, C-reactive protein; SLEDAI-2K, systemic lupus erythematosus disease activity index-2000