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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Salivary anti-nuclear antibody (ANA) mirrors serum ANA in systemic lupus erythematosus

Fig. 1

Salivary ANA positivity and IF intensity were significantly higher in SLE patients than in HC. A Correlation of salivary ANA observer score (OS) and ImageJ score (IS) for ANA IF intensity. Salivary ANA OS represents the average observer score of four observers. B ANA IF intensity was significantly higher in SLE patients (n = 70) than in HC (n = 10), C irrespective of the disease status of SLE patients (less active SLE, n = 38; active SLE, n = 32). D ROC analysis illustrating the ability of saliva ANA IF intensities to differentiate SLE patients from HC. E ANA positivity of SLE and HC defined by the cutoff value of OS ≥ 0.75. F Saliva ANA OS was significantly correlated with serum ANA titer. *P < 0.05, **P < 0.01, ***P < 0.001. ANA, anti-nuclear antibodies; IF, immunofluorescence; HC, healthy controls

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