Fig. 4

Correlation of salivary ANA and ANA isotypes with clinical parameters in SLE patients. Salivary ANA OS represents the average score from four observers. Both salivary ANA OS and IS indicate the immunofluorescent intensity of salivary ANA, whereas salivary IgM-ANA, IgG-ANA, and IgA-ANA reflect the ELISA-assayed concentrations of the ANA isotypes. The number of SLE patients assayed was 70. Analysis was done using Spearman correlation. Yellow and blue circles represent positive and negative correlation coefficient, respectively, with larger circles indicating stronger correlation. ESR, erythrocyte sedimentation rate; IS, Image J score; OS, observer score; PGA, physician global assessment; SLEDAI, systemic lupus erythematosus disease activity index