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Table 2 Associations of glucocorticoid use with APOs, PB, LBW, and LFD

From: Preterm birth is strongly affected by the glucocorticoid dose during pregnancy in women complicated by systemic lupus erythematosus

 

APOs

PB

LBW

LFD

APOs (+)

(n = 35)

APOs (−)

(n = 34)

P value

PB (+)

(n = 14)

PB (−)

(n = 45)

P value

LBW (+)

(n = 23)

LBW (−)

(n = 36)

P value

LFD (+)

(n = 10)

LFD (−)

(n = 49)

P value

Glucocorticoid use, n (%)##

31 (88.6)

25 (73.5)

0.13

13 (92.9)

36 (80.0)

0.42

23 (100.0)

26 (72.2)

<  0.01*

10 (100.0)

39 (79.6)

0.19

Mean glucocorticoid dose, mg/day#

9.6 ± 5.0

6.6 ± 3.7

0.03*

12.3 ± 5.5

6.7 ± 3.3

<  0.01*

9.5 ± 4.9

7.1 ± 4.2

0.05

10.0 ± 5.7

7.8 ± 4.3

0.26

Increase in the glucocorticoid dose, n (%)##

11 (31.4)

2 (5.9)

0.01*

9 (64.3)

3 (6.7)

<  0.01*

9 (39.1)

3 (8.3)

<  0.01*

2 (20.0)

10 (20.4)

1.00

  1. Values are shown as mean ± standard deviation or n (%). #Wilcoxon rank sum test; ##Fisher’s exact test; *P < 0.05. APOs adverse pregnancy outcomes, PB preterm birth, LBW low birth weight, LFD light-for-date