Fig. 3
From: Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis
HCQ delays renal repair in the mice with proteinuric LN after AKI. A Representative immunohistochemical staining of renal E-cadherin in the mice with proteinuric LN subjected to I/R-induced AKI. B Quantitative analysis of renal E-cadherin in the mice with proteinuric LN. C Western blotting of renal E-cadherin in the mice with proteinuric LN. D Quantitative analysis of renal E-cadherin expression in the mice with proteinuric LN subjected to I/R-induced AKI by Western blotting. E Representative immunohistochemical staining and renal PCNA and Ki67 staining of the mice with proteinuric LN subjected to I/R-induced AKI. F, G Quantitative analysis of renal PCNA and Ki67 in the mice with proteinuric LN subjected to I/R-induced AKI. H Western blotting analysis of renal PCNA in the mice with proteinuric LN. I Quantitative analysis of renal PCNA expression in the mice with proteinuric LN by Western blotting. J CCK-8 analysis of the proliferation of HK-2 cells. K CFSE staining and flow cytometric analysis of HK-2 cells. Each bar represents the mean ± SEM, with more than 5 mice in each group at each time point. *P < 0.05, **P < 0.01, and ***P < 0.001. Original magnification × 200