Fig. 4

HCQ promotes PTEC apoptosis in the mice with proteinuric LN subjected to AKI. A Representative renal TUNEL staining images of the mice with proteinuric LN subjected to cisplatin-induced AKI. B Quantitative analysis of renal TUNEL staining of the mice with proteinuric LN subjected to cisplatin-induced AKI. C Western blotting of renal caspase-9 expression in the mice with proteinuric LN subjected to cisplatin-induced AKI. D Quantitative analysis of renal caspase-9 expression in the mice with proteinuric LN subjected to cisplatin-induced AKI by Western blotting. E Representative renal TUNEL staining images of the mice with proteinuric LN subjected to I/R-induced AKI. F Quantitative analysis of renal TUNEL staining in the mice with proteinuric LN subjected to I/R-induced AKI. G Western blotting of renal BAX expression in the mice with proteinuric LN subjected to I/R-induced AKI. H Quantitative analysis of renal BAX expression in the mice with proteinuric LN subjected to I/R-induced AKI by Western blotting. Each bar represents the mean ± SEM. In the cisplatin-induced AKI experiments, there were more than 7 mice in each group; in the I/R-induced AKI experiments, there were more than 5 mice in each group at each time point. *P < 0.05, **P < 0.01, and ***P < 0.001. Original magnification × 200