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Table 2 Participant reproductive history and perinatal medication use descriptions

From: “The medications are the decision-makers…” Making reproductive and medication use decisions among female patients with rheumatoid arthritis: a constructivist grounded theory

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Pregnancy history

Medication use

Reproductive goals

Reproductive decision-making processd

Preconception

Pregnancy

Post-partum

P01

Never pregnant

   

To have children

Having children

P02

Never pregnant

   

To have children

Having children

P03

Never pregnant

   

To have children

Having children

P04

Never pregnant

Restarted MTX

  

To have children

Planning pregnancy, using medications

P05

Never pregnant

Using HCQ [↑ RA activity]

  

To have children

Planning pregnancy, using medications

P06

Never pregnant

Using chloroquinec

  

To have children

Pregnancy planningc

P07

Never pregnant

   

Finished growing family

 

P08

No previous pregnancy, pregnant

 

Started HCQc and prednisone [↓ RA activity]

 

Intending to have children

Planning pregnancyc

P09

No previous pregnancy, pregnant

Stopped MTX, HCQ, SZS; started certolizumab pegol

Using certolizumab pegol [low RA activity]

 

To have children

Planning pregnancy

P10

Previous pregnancya; 1 child

Stopped MTX; started certolizumab pegol

Used certolizumab pegol

Started MTX(?), stopped breastfeeding

To have children

Planning pregnancy

P11

Previous pregnancya; 1 child

Stopped MTX, HCQ, SZS

Used prednisone; [high RA activity]

Started certolizumab pegol, delayed MTX to breastfeed

Finished growing family

 

P12

Previous pregnancya; 1 child

Used MTX and etanercept

Stopped MTX in T1; used etanercept, prednisone [high RA activity]

Started MTX, stopped breastfeeding

Finished growing family

 

P13

Previous pregnancya; 2b children

Stopped SZS

Used prednisone [high RA activity]

Started MTX, stopped breastfeeding

Finished growing family

 

P14

Previous pregnanciesa, 2 children

1st: used etanercept until conception

2nd: Used etanercept

1st: no medication; [high RA activity]

2nd: Used etanercept [low RA activity]

1st: used etanercept; did not breastfeed

2nd: used etanercept; did not breastfeed

Finished growing family

 

P15

Previous pregnanciesa; 2 children

1st: cDid not start DMARDs

2nd: Stopped HCQ

1st: no medication; [low RA activity]

2nd: no medication; [high RA activity]

1st: breastfeeding? [High RA activity]

2nd: Started tDMARDs; breastfeeding?

Finished growing family

 

P16

Previous pregnanciesa; 2 children

1st: Stopped LEF, MTX

2nd: Used prednisone

1st: Used prednisone

2nd: Used prednisone

2nd: Started DMARDs after breastfeeding

Finished growing family

 

P17

Previous pregnancies; no children

cUsing SZS, HCQ; intending to start bDMARD

  

Intending to have children

Having children

P18

Previous pregnancies; 4 children

  

Delayed MTXc to breastfeed

To have children

Having children

P19

Previous pregnancy; 4 children

Using HCQ, etanercept

  

To have children

Planning pregnancy

P20

Previous pregnancy; 3b children

  

Using HCQc, SZS; delaying MTX to breastfeed

Finished growing family

Parenting

P21

Previous pregnancy; 1 child

c

  

Finished growing family

Parenting

  1. Abbreviations: bDMARDs biologic DMARDs, DMARDs disease-modifying anti-rheumatic drugs, tDMARDs targeted DMARDs, HCQ hydrochloroquine, LEF leflunomide, MTX methotrexate, RA rheumatoid arthritis, SZS sulfasalazine
  2. aDiagnosed with RA during one or more previous pregnancy experiences
  3. bOne child was not carried by participant through pregnancy (i.e., adopted or joined family through marriage)
  4. cIndicates timing of receiving RA diagnosis if within the perinatal period
  5. dRelative to the timing of the interview with participant