Skip to main content

Table 1 Baseline characteristics of the patients

From: Latent class analysis of 216 patients with adult-onset Still’s disease

 

Total (n=216)

Relapse (n=76)

Non-relapse (n=140)

General characteristics

 Age, median years [IQR]

51.6 [33.1–68.1]

50.3 [30.2–65.9]

47.9 [31.8–69.9]

 Female, n (%)

164 (75.9%)

68 (89.4%)

59 (65.6%)

 Follow-up time, median months [IQR]

36.8 [12.1–88.2]

80.6 [40.0–135.8]

18.8 [8–46.8]

Proportion of patients with the specific symptom

 Fever, %

99.5%

100.0%

98.9%

 Rash, %

90.7%

97.3%

87.1%

 Abnormal liver function tests, %

81.0%

85.5%

76.9%

 Arthralgia, %

79.5%

82.6%

77.8%

 Sore throat, %

63.3%

56.1%

67.1%

 Lymphadenopathy, %

63.5%

60.0%

65.9%

 Splenomegaly, %

49.5%

47.8%

50.4%

 Chest pain, %

1.9%

1.3%

2.1%

 Abdominal pain, %

1.9%

1.3%

2.1%

Laboratory tests

 White blood cell count, median /μL [IQR]

12600 [9400–18100]

12600 [9190–17975]

12630 [9575–18100]

 Neutrophil count, median /μL [IQR]

10677 [7555–15794]

10583 [7235–16194]

10677 [7665–14960]

 Hemoglobin, median g/dL [IQR]

11.1 [10.1–12.4]

10.8 [9.8–11.7]

11.3 [10.2–12.7]

 Platelet, median /μL [IQR]

258 [163–366]

260 [170–351]

256 [159–377]

 Erythrocyte sedimentation rate, median mm/h [IQR]

76 [41–94]

80 [40–95]

75 [44–92]

 Serum aspartate aminotransferase, median U/L [IQR]

69 [46–128]

68 [47–125]

69 [45–130]

 Serum alanine aminotransferase, median U/L [IQR]

52 [30–104]

50 [25–87]

53 [31–110]

 Serum lactate dehydrogenase, median U/L [IQR]

521 [314–761]

587 [357–796]

501 [303–734]

 Serum C-reactive protein, median mg/dL [IQR]

10.8 [5.7–16.6]

11 [5.8–18.6]

10.8 [5.7–14.8]

 Serum ferritin, median ng/mL [IQR]

7230 [2002–22065]

8536 [1745–29940]

6190 [2201–18472]

Complications

 Macrophage activation syndrome, %

22.3%

18.4%

24.5%

 Disseminated intravascular coagulation, %

13.4%

17.1%

11.5%

 Renal dysfunction, %

3.7%

3.9%

3.6%

 Pleuritis, %

12.5%

10.7%

13.6%

 Pericarditis, %

7.4%

4.0%

9.3%

 Myocarditis, %

0.0%

0.0%

0.0%

 Interstitial pneumonia, %

2.3%

2.7%

2.1%

  1. IQR interquartile range