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Table 2 The difference in blood lipid and cardiovascular risk parameters between psoriasis with and without psoriatic arthritis and healthy controls

From: The difference of lipid profiles between psoriasis with arthritis and psoriasis without arthritis and sex-specific downregulation of methotrexate on the apolipoprotein B/apolipoprotein A-1 ratio

 

PsA (n=136)

HC1 (n=136)

PsA vs HC1

p-value

PsO (n=152)

HC2 (n=152)

PsO vs HC2

p-value

PsA vs PsO

p-value

ApoA1, g/L

1.08 (0.18)

1.21 (0.17)

<.0001

1.07 (0.18)

1.20 (0.16)

<.0001

.4496

ApoB, g/L

0.76 (0.15)

0.65 (0.13)

<.0001

0.70 (0.17)

0.60 (0.12)

<.0001

.0013

TC, mmol/L

4.95 (0.89)

4.82 (0.82)

.1939

4.61 (0.89)

4.56 (0.71)

.6033

.0013

TG, mmol/L

1.74 (1.13)

1.45 (1.07)

.0347

1.57 (1.02)

1.29 (0.86)

.0098

.1894

HDL-C, mmol/L

1.23 (0.32)

1.26 (0.26)

.3967

1.21 (0.29)

1.27 (0.27)

.037

.4731

LDL, mmol/L

3.06 (0.77)

2.83 (0.70)

.0115

2.84 (0.81)

2.67 (0.65)

.0405

.0229

Lp(a), mg/L

147.9 (158.0)

121.5 (138.8)

.1443

139.6 (175.2)

125.0 (150.0)

.4364

.6747

ApoB:ApoA1 ratio

0.72 (0.19)

0.55 (0.13)

<.0001

0.67 (0.19)

0.51 (0.13)

<.0001

.0208

TC:HDL ratio

4.21 (1.07)

3.94 (0.92)

.0227

3.98 (1.03)

3.73 (0.92)

.0261

.0603

LDL:HDL ratio

2.62 (0.82)

2.31 (0.67)

.0009

2.47 (0.85)

2.19 (0.71)

.0022

.1309

LDL:ApoB ratio

4.03 (0.59)

4.37 (0.69)

<.0001

4.08 (0.56)

4.41 (0.55)

<.0001

.4869

  1. Abbreviation: ApoA1 apolipoprotein A1, ApoB apolipoprotein B, HC healthy controls, HDL-C high-density lipoprotein-cholesterol, LDL low-density lipoprotein, Lp(a) lipoprotein A, PsA psoriatic arthritis, PsO psoriasis without arthritis, TC total cholesterol, TG triglyceride
  2. Mann-Whitney test, unpaired t test, and unpaired t test with Welch correction were used when appropriate. p < .025 is considered to be statistically significant