Table 2 Baseline predictors for progression to IA in anti-CCP+ individuals

Mean age (SD; range)

50 (15.65; 18–77)

54 (14.39; 23–83)

1.01 (0.99–1.03) P = 0.136

0.95 (0.95–1.02) P = 0.504

Female (%)

66

56

0.64 (0.33–1.24) P = 0.193

0.56 (0.21–1.45) P = 0.234

CCP high level (%)

45

90

10.83 (4.43–26.48) P < 0.001

9.42 (3.13–28.30) P < 0.001

Family with RA (%)

58

47

0.64 (0.34–1.23) P = 0.188

0.56 (0.24–1.34) P = 0.198

Ever smoked (%)

55

72

2.07 (1.04–4.11) P = 0.037

2.37 (0.96–5.83) P = 0.060

Neck (%)

30

22

0.65 (0.72–3.19) P = 0.266

0.39 (0.13–1.13) P = 0.086

Shoulders (%)

47

56

1.18 (0.13–1.37) P = 0.277

0.90 (0.35–2.36) P = 0.844

Elbows (%)

28

27

0.93 (0.45–1.93) P = 0.865

0.93 (0.33–2.62) P = 0.894

Wrists (%)

43

66

2.55 (1.31–4.96) P = 0.006

1.28 (0.49–3.36) P = 0.607

Hands (%)

47

81

4.77 (2.27–10.02) P < 0.001

2.74 (1.03–7.27) P = 0.043

Thumbs (%)

29

40

1.61 (0.82–3.19) P = 0.164

1.34 (0.44–4.06) P = 0.599

Back (%)

23

13

0.51 (0.21–1.22) P = 0.133

0.68 (0.20–2.25) P = 0.532

Hips (%)

31

29

0.91 (0.45–1.83) P = 0.799

1.33 (0.51–3.46) P = 0.557

Knees (%)

46

56

1.50 (0.78–2.85) P = 0.218

1.08 (0.44–2.69) P = 0.855

Ankles (%)

30

32

1.11 (0.55–2.21) P = 0.768

0.80 (0.27–2.41) P = 0.701

Feet (%)

29

62

3.97 (2.00–7.85) P < 0.001

4.10 (1.59–10.54) P = 0.003