Fig. 3

Time to initial MDA response: a OPAL Broaden, b OPAL Beyond (FAS). Response defined for MDA as meeting ≥ 5 of 7 of the following disease activity outcome criteria: tender joint count ≤ 1; swollen joint count ≤ 1; Psoriasis Area and Severity Index score ≤ 1 or body surface area ≤ 3%; Patient’s Assessment of Arthritis Pain VAS ≤ 15 mm; Patient’s Global Assessment of Arthritis VAS ≤ 20 mm; Health Assessment Questionnaire-Disability Index score ≤ 0.5; or tender entheseal points (using the Leeds Enthesitis Index) ≤ 1 [23]. BID, twice daily; FAS, full analysis set; MDA, minimal disease activity; Q2W, once every 2 weeks; SC, subcutaneous; VAS, visual analog scale