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Table 1 Patient characteristics

From: Tumor necrosis factor alpha neutralization attenuates immune checkpoint inhibitor-induced activation of intermediate monocytes in synovial fluid mononuclear cells from patients with inflammatory arthritis

Patient characteristics

Diagnosis

RA (n = 14)

Peripheral SpA (n = 9)

PsA (n = 5)

Age (years)

53 (36.5– 59)

40 (33–43)

45 (35–49)

Gender (females)

5

4

3

Disease activity

 CRP (mg/L)

19 (8.7–20.75)

16.25 (5.5–44.13)

4 (3–5)

 DAS28CRP

3.71 (3.19–4.12)

3.50 (2.90–4.66)

3.01 (2.79–3.68)

 Swollen joint count

1 (1–2.75)

1.5 (1–2)

1.5 (0.75–5.25)

 Tender joint count

1 (1–2.5)

1 (1–2)

1.5 (0.75–3)

 Disease duration (years)

11 (5–18)

2 (0.5–15)

14 (5–14)

 RF positive (n)

4

0

0

 Anti-CCP positive (n)

4

0

0

 HLA-B27 (n)

5

Treatment

csDMARDs

  MTX (n)

10

2

3

  Salazopyrine (n)

3

3

0

bDMARDs

  TNF-inhibitor (n)

4

4

1

No DMARDs (n)

2

4

2

  1. Data are expressed as median and IQR
  2. Missing data (n): age (1), gender (1), CRP (1), patient global VAS (6), swollen joint count (1), tender joint count (1), disease duration (1), RF (1), anti-CCP (1), treatment (1)
  3. Abbreviations: RA rheumatoid arthritis, SpA spondyloarthritis, PsA psoriatic arthritis, CRP C-reactive protein, DAS28CRP Disease Activity Score 28 based on CRP, RF rheumatoid factor, Anti-CCP antibodies targeting citrullinated peptides, csDMARDs conventional synthetic disease-modifying anti-rheumatic drugs, bDMARDs biologic disease-modifying anti-rheumatic drugs, IQR interquartile range