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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Chondrocyte-derived exosomes promote cartilage calcification in temporomandibular joint osteoarthritis

Fig. 4

The expression of calcification inhibitor was decreased in condylar cartilage, while the expression of calcification promotors was increased. A The number of MGP-positive chondrocytes and the mRNA expression of Mgp were decreased in the condylar cartilage of UAC rats (n = 6). B The number of TNAP-positive chondrocytes and the mRNA expression of Tnap were decreased in the condylar cartilage of UAC rats (n = 6). C The number of NPP1-positive chondrocytes and the mRNA expression of Npp1 were decreased in the condylar cartilage of UAC rats (n = 6). Scale bar = 100 μm. Control, control group; UAC, unilateral anterior crossbite group; 4w, 4 weeks; 8w, 8 weeks; 12w, 12 weeks. All data are presented as means ± SD. The data of compared groups were from the populations of Gaussian distribution and consistent with homogeneity of variance. Comparisons between the control and UAC groups of the same timepoint were performed by Student’s t test. **P < 0.01, compared with the age-matched control group

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