Clinical Parameters | Patients with TAK | Healthy controls (n = 48) | |||
---|---|---|---|---|---|
Total (n = 50) | For chemokine screening (n = 5) | For chemokine validation (n = 45) | p | ||
General information | |||||
 Gender ratio (F:M) | 41:9 | 5:0 | 36:9 | 057 | 36:12 |
 Age at diagnosis (mean ± SD, y) | 34.40 ± 13.25 | 28.80 ± 6.61 | 35.07 ± 13.69 | 0.32 | / |
 Disease duration (months) | 6.00 (2.00–15.00) | 12.00 (1.50–30.0a0) | 6.00 (2.00–12.00) | 0.68 | / |
 Active disease status (n, %) | 40 (80.00) | 3 (60) | 37 (82.22) | 0.26 | / |
Clinical symptoms | |||||
 Weakness (n, %) | 11 (22.00) | 2 (40) | 9 (20.00) | 0.30 | / |
 Fever (n, %) | 6 (12.00) | 1 (20) | 5 (11.11) | 0.49 | / |
 Hypertension (n, %) | 14 (28.00) | 1 (20) | 13 (28.89) | 1.00 | / |
 Claudication (n, %) | 2 (4.00) | 0 (0) | 2 (4.44) | 1.00 | / |
 Chest distress (n, %) | 9 (18.00) | 0 (0) | 9 (20.00) | 0.57 | / |
 Dizziness (n, %) | 24 (48.00) | 3 (60) | 21 (46.67) | 0.66 | / |
 Pulselessness/weak pulse (n, %) | 17 (34.00) | 2 (40) | 15 (33.33) | 1.00 | / |
 Vascular bruits (n, %) | 17 (34.00) | 3 (60) | 14 (31.11) | 0.32 | / |
Lab results | |||||
 Hemoglobin (mean ± SD, g/L) | 119.41 ± 15.20 | 115.00 ± 13.93 | 119.62 ± 15.35 | 0.50 | 132.69 ± 13.42 |
 WBC (mean ± SD, 109/L) | 8.99 ± 5.87 | 9.51 ± 2.47 | 8.95 ± 6.10 | 0.97 | 6.23 ± 2.06 |
 PLT (mean ± SD, 109/L) | 293.47 ± 93.70 | 346.25 ± 140.67 | 288.78 ± 89.18 | 0.12 | 258.46 ± 61.55 |
 ESR (mean ± SD, mm/H) | 44.18 ± 30.18 | 59.50 ± 31.69 | 42.82 ± 30.04 | 0.29 | / |
 CRP (mean ± SD, mg/L) | 24.40 ± 26.69 | 32.13 ± 26.18 | 23.71 ± 26.92 | 0.55 | / |
 IL-6 (mean ± SD, pg/ml) | 11.80 ± 10.26 | 12.54 ± 10.28 | 11.71 ± 10.38 | 0.87 | / |
 TNF-α (mean ± SD, pg/ml) | 8.94 ± 7.99 | 4.93 ± 0. 68 | 9.42 ± 8.33 | 0.29 | / |
Imaging type | |||||
 I | 13 (26.00) | 4 (80) | 9 (20.00) | 0.028 | / |
 IIa | 2 (4.00) | 0 (0) | 2 (4.44) | / | |
 IIb | 8 (16.00) | 0 (0) | 8 (17.78) | / | |
 III | 1 (2.00) | 0 (0) | 1 (2.22) | / | |
 IV | 5 (10.00) | 1 (20) | 4 (8.89) | / | |
 V | 22 (48.89) | 0 (0) | 22 (46.67) | / |