Treatment of gouty arthritis is associated with restoring the gut microbiota and promoting the production of short-chain fatty acids

Table 1 Characteristics of study participants with gouty arthritis according to disease states

Characteristics	Acute state	Recovery state
Age	63.90 ± 14.90^a
Sex, male (%)	19 (95.0)
Follow-up duration, days	64.50 ± 25.66
Uric acid	6.77 ± 1.96^†	5.32 ± 1.74^†
eGFR	71.90 ± 19.98	71.10 ± 16.83
ESR (mm/h)	49.94 ± 34.36^‡	19.88 ± 19.50^‡
CRP (mg/dl)	5.13 ± 6.90^§	0.35 ± 0.54^§
Involved joints at attack
First MTP joint	8 (40.0)
Knee/ankle	7 (35.0)/3 (15.0)
Wrist/elbow	2 (10.0)/2(10.0)
No. of involved joints at attack
1	14 (70.0)
2	1 (5.0)
≥ 3	5 (25.0)
Treatment agents, n (%)
Colchicine	20 (100.0)
NSAID	7 (35.0)
Corticosteroid	4 (20.0)
Intraarticular injection	9 (45.0)
Urate lowering agents
Febuxostat	14 (70.0)
Allopurinol	1 (5.0)
Benzbromarone	1 (5.0)

Data are expressed as means ± SD for continuous variables or numbers and percentages for categorical variables
eGFR estimated glomerular filtration rates, ESR erythrocyte sedimentation rate, CRP C-reactive proteins, MTP metatarsophalangeal, No. number, NSAID non-steroidal anti-inflammatory drugs
^aOf the 20 patients, two patients received antibiotics for 3 days at the time of acute state
^†n = 19, p = 0.010
^‡n = 17, p = 0.001
^§p < 0.001

ISSN: 1478-6362