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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Preferable outcome of Janus kinase inhibitors for a group of difficult-to-treat rheumatoid arthritis patients: from the FIRST Registry

Fig. 3

Time trend of clinical parameters. A Fluctuation of the average values with standard errors of CDAI in the time trend. B Fluctuation of the average values with standard errors of HAQ-DI in the time trend. C Time trend of the proportion of remission in the b/tsDMARD-naïve group, the 1 class failure group, and the D2T RA group. CDAI, Clinical Disease Activity Index; HAQ-DI, Health Assessment Questionnaire Disability Index; D2T RA, difficult-to-treat rheumatoid arthritis, b/tsDMARD, targeted synthetic disease-modifying anti-rheumatic drugs; TNFi, tumour necrosis factor inhibitor; IL-6Ri, interleukin-6 receptor inhibitor; CTLA4-Ig, cytotoxic T-lymphocyte-associated antigen-4 immunoglobulin; JAKi, Janus kinase inhibitor

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