Factors affecting patient satisfaction related to cost and treatment effectiveness in rheumatoid arthritis: results from the multicenter observational cohort study, FRANK Registry

Table 6 Results of the instrumental variable analysis for each aspect of satisfaction

Satisfaction	Model	Interacted factors	p-value for interaction
Cost of treatment	Subjective model	Disease duration and EQ5D	< 0.001
	Subjective model	Pain VAS and EQ5D	0.004
	Objective model	Age and b/tsDMARDs use	0.011
		Sex and log-transformed CRP	< 0.001
		Disease duration and history of musculoskeletal surgery	0.011
		Log-transformed CRP and physician VAS	0.012
		History of musculoskeletal surgery and methotrexate use	0.026
		History of musculoskeletal surgery and b/tsDMARDs use	< 0.001
Effect of treatment	Subjective model	Disease duration and EQ5D	0.007
	Subjective model	General VAS and EQ5D	0.013
	Objective model	TJC and history of musculoskeletal surgery	0.020
		Age and methotrexate use	0.031
		SJC and methotrexate use	0.002
		Physician VAS and methotrexate use	< 0.001
ADL	Subjective model	Disease duration and sex	0.017
		Pain VAS and EQ5D	0.024
		General VAS and EQ5D	0.030
	Objective model	History of musculoskeletal surgery and Steinbrocker stage	0.004
	Objective model	Methotrexate use and b/tsDMARDs use	0.022
Global treatment	Subjective model	General VAS and EQ5D	< 0.001
	Objective model	Age and Steinbrocker stage	0.022
		Age and b/tsDMARDs use	0.005
		TJC and physician VAS	0.004

ISSN: 1478-6362