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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Using real-world data to dynamically predict flares during tapering of biological DMARDs in rheumatoid arthritis: development, validation, and potential impact of prediction-aided decisions

Fig. 2

Mean DAS28-trajectories of identified latent classes and their relation to the occurrence of a flare. A The mean course of the disease activity score (DAS28) over time in patients assigned to one of the two “latent trajectory classes.” In class 1 (n = 182), a stable low disease activity is observed, whereas patients in class 2 (n = 97) display an increasing disease activity over time. B The probability of remaining free from flares over time for patients assigned to one the “latent trajectory classes” for disease activity, as displayed on the left. Patients in class 2 display a shorter time to flare as compared to patients in class 1

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