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Table 1 Comparison of the clinicopathological findings in patients with and without extraophthalmic lesions of the head and neck

From: Pathological count of IgG4-positive plasmacytes suggests extraophthalmic involvement and relapse in patients with IgG4-related ophthalmic disease: a retrospective study

Clinicopathological factor

Extraophthalmic lesions of head and neck

p value

With (n = 16, 29.1%)

Without (n = 39, 70.9%)

Age of disease onset (years)

54.1 ± 10.7

51.8 ± 12.5

0.298

Sex (male, %)

51.3

62.5

0.448

Bilaterality (%)

75

38.5

0.014*

Lacrimal gland involvement (%)

87.5

74.4

0.284

ln (serum IgG4 level)

6.8 ± 0.7

5.2 ± 1.2

< 0.001*

GC (LPF)

6.7 ± 2.5

5.3 ± 2.9

0.099

Pathological IgG4+ plasmacyte (HPF)

161.9 ± 49.5

113.1 ± 58.1

0.005*

Pathological IgG+ plasmacyte (HPF)

201.2 ± 64.0

185.4 ± 77.9

0.476

Pathological IgG4+/IgG+ ratio (%)

82.8 ± 11.5

63.6 ± 22.5

0.002*

  1. ln natural logarithm, GC germinal center, *p < 0.05