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Table 2 Comparison of the clinicopathological findings in IgG4ROD patients with and without relapse after steroid treatment

From: Pathological count of IgG4-positive plasmacytes suggests extraophthalmic involvement and relapse in patients with IgG4-related ophthalmic disease: a retrospective study

Clinicopathological factor

Relapse after steroid treatment

p Value

With (n = 24, 58.5%)

Without (n = 17, 41.5%)

Age of disease onset (years)

54.7 ± 8.5

48.8 ± 16.3

0.135

Sex (male, %)

50.0

47.1

0.853

Bilaterality (%)

62.5

47.1

0.326

Lacrimal gland involvement (%)

79.2

76.5

0.837

ln (serum IgG4 level)

6.4 ± 0.99

5.0 ± 1.26

0.002*

GC (LPF)

7.2 ± 2.7

4.0 ± 2.4

< 0.001*

Pathological IgG4+ plasmacyte (HPF)

155.7 ± 51.2

94.6 ± 49.0

< 0.001*

Pathological IgG+ plasmacyte (HPF)

199.42 ± 58.5

167.0 ± 74.4

0.127

Pathological IgG4+/IgG+ ratio (%)

80.4 ± 16.2

59.9 ± 21.8

0.001*

Systemic involvement (head and neck, %)

45.8

23.5

0.144

  1. ln natural logarithm, GC germinal center, *p < 0.05