Fig. 2
From: Lupus nephritis correlates with B cell interferon-β, anti-Smith, and anti-DNA: a retrospective study
Association of clinical and laboratory parameters with B cell IFNβ in SLE patients. Eighty SLE patients were analyzed for B cell IFNβ and other clinical and laboratory characteristics. A Principal component (PC) analysis of 18 parameters and B cell IFNβ. The clinical parameters indicated near the position of the PC analysis plot and the p value of each parameter as being associated with B cell IFNβ is shown in the parenthesis. Variants shown in red exhibit significant positive correlation with B cell IFNβ. Variants shown in blue exhibit significant negative correlation with B cell IFNβ. B Linear regression analysis of anti-Smith (top) and anti-DNA (bottom) with B cell IFNβ. Anti-Sm was shown as U/mL. Anti-DNA was shown as OD450. R2, p value, and number of subjects (n) are indicated. C–E Bar graph showing the percentages of IFNβ+ naïve B cells in SLE patients with (positive) or without (negative) LN (C), photosensitivity (D), and oral/nasal ulcer (E) (mean ± SD; unpaired t-test with the p value shown in each panel)