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Table 4 Univariate logistic regression analysis of risk factors for all complications of cervical spine surgery in patients with RA

From: Risk factor analysis of perioperative complications in patients with rheumatoid arthritis undergoing primary cervical spine surgery

 

No complication

Complication

Univariable

(111)

(28)

OR (95% CI)

p value

Age, years

66.1 ± 9.60

68.0 ± 11.4

1.019 (0.977–1.063)

.379

Sex, male/female, n

30/81

5/23

1.704 (0.594–4.888)

.322

Height, m

1.532 ± 0.089

1.479 ± 0.091

0.928 (0.880–0.980)

.007

Weight, kg

51.6 ± 11.1

49.2 ± 13.2

0.982 (0.946–1.019)

.327

BMI, kg/m2

21.8 ± 3.7

22.3 ± 4.7

1.029 (0.925–1.144)

.602

BSA, m2

1.43± 0.18

1.37 ± 0.21

0.128 (0.011–1.428)

.095

Serum albumin, g/dl

3.72 ± 0.48

3.60 ± 0.46

0.594 (0.247–1.428)

.243

Charlson comorbidity index

1.73 ± 1.02

1.68 ± 0.86

0.947 (0.614–1.460)

.806

ASA-PS

2.29 ± 0.49

2.50 ± 0.51

2.296 (1.007–5.235)

.048

Disease duration, years

20.2 ± 14.5

17.6 ± 12.1

0.986 (0.955–1.017)

.363

CRP, mg/dl

1.07 ± 1.20

1.12 ± 1.37

0.972 (0.707–1.337)

.862

Medication

 Biologics/JAK inhibitor, n (%)

13 (11.7)

5 (17.9)

1.639 (0.531–5.058)

.390

 Methotrexate, n (%)

46 (41.4)

11 (39.3)

0.914 (0.392–2.133)

.836

 Methotrexate, mg

2.67 ± 0.35

2.29 ± 0.59

0.969 (0.858–1.095)

.612

 Prednisolone, n (%)

92 (82.9)

26 (92.9)

2.685 (0.587–12.28)

.203

 Prednisolone, mg

4.79 ± 0.33

5.73 ± 0.52

1.083 (0.961–1.221)

.193

Cervical spine lesion

 AAS, n (%)

73 (65.8)

19 (67.9)

1.099 (0.454–2.662)

.834

 VS, n (%)

42 (38.2)

18 (64.3)

2.914 (1.229–6.911)

.015

 SAS, n (%)

28 (25.7)

13 (46.4)

2.507 (1.063–5.913)

.036

Operation time, minutes

134.3 ± 43.3

167.1 ± 62.4

1.013 (1.004–1.021)

.003

Bleeding volume, g

72.5 ± 79.2

124.0 ± 177.5

1.004 (1.000–1.007)

.040

Procedure

 Laminoplasty, n (%)

55 (49.6)

8 (28.6)

Ref

Ref

 C1/2 fusion, n (%)

30 (27.0)

3 (10.7)

0.688 (0.170–2.787)

.600

 OC fusion, n (%)

20 (18.0)

10 (35.7)

3.438 (1.189–9.934)

.023

 Long fusion, n (%)

6 (5.4)

7 (25.0)

8.021 (2.145–29.99)

.002

  1. Mean ± standard deviation (SD)
  2. OR odds ratio, CI confidence interval, Ref reference, BMI body mass index, CRP C-reactive protein, ASA-PS American Society of Anesthesiologists Physical Status, AAS atlantoaxial subluxation, VS vertical subluxation, SAS subaxial subluxation, C1/2 fusion atlantoaxial fusion, OC fusion occipito-cervical fusion