Healthy | Non-severe | Severe | p-value | |
---|---|---|---|---|
n | 15 | 15 | 16 | - |
Age (years) | 50.3±9.0 | 59.7±17.2 | 61.9±17.0 | 0.66 |
Sex (% female) | 100% | 100% | 100% | NA |
Duration from onset (years) | - | 5.7±10.2a | 14.8±10.9a | 0.064 |
Duration from diagnosis (years) | - | 5.7±7.0 | 9.8±7.2b | 0.079 |
BMI | - | 25.6±4.6b | 25.3±6.2b | 0.88 |
Stimulated salivary flow rate | - | 7.2±3.1 ml/5 min | 1.5±0.9 ml/5 min | 6.66 × 10-9 |
Schirmer right (mm/5 min) | - | 8.0±9.3 | 5.5±5.9b | 0.69 |
Schirmer left (mm/5 min) | - | 7.9±7.4 | 6.5±7.0b | 0.61 |
Anti-SSA | - | 11/73.3% | 13/86.7%c | 0.39 |
Anti-SSB | - | 2/13.3% | 5/33.3%c | 0.21 |
Seropositive (SSA and/or SSB) | - | 11/73.3% | 13/86.7%c | 0.39 |
cMARD | - | 5/35.7%d | 4/33.3%e | 0.93 |
bMARD (anti-TNF) | - | 0/0.0%f | 0/0.0%a | NA |
Glucocorticoid | - | 3/21.4%d | 1/9.1%g | 0.44 |
Cyclosporine eye drops | - | 3/37.5%h | 3/33.3%f | 0.91 |
Oral pilocarpine | - | 1/14.3%i | 1/12.5%h | 1 |
Natural tears | - | 4/40.0%j | 2/28.6%i | 0.68 |
Angina pectoris | - | 1b | 0e | 0.38 |
Autoimmune thyroid disease | - | 0 | 2 | 0.18 |
Gynaecologic manifestation | - | 1b | 0e | 0.38 |
Anemia | - | 2b | 0e | 0.18 |
Leukopenia | - | 1b | 1e | 1 |
Neutropenia | - | 1b | 0e | 0.38 |
Cancer | - | 1b | 1e | 1 |