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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Effects of local cryotherapy on systemic endothelial activation, dysfunction, and vascular inflammation in adjuvant-induced arthritis (AIA) rats

Fig. 2

Expression of endothelial activation markers in AIA rats and effect of cryotherapy. AG Effect of AIA on aortic mRNA expression of markers of endothelial activation as compared to control rats on day 24 post-immunization. HN Effect of a daily treatment with local cryotherapy in AIA rats. Endothelial activation was assessed in thoracic aorta by measuring by qRT-PCR the mRNA expression of IL-6 (A, H), TNF-α (B, I), CXCL-1 (C, J), ICAM-1 (D, K), VCAM-1 (E, L), MCP-1 (CCL-2) (F, M) and MIP-1α (CCL-3) (G, N). Results are expressed as means ± SEM (n=number of rats/group). *(p<0.05), **(p<0.01). NS, non-significant

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