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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Effects of local cryotherapy on systemic endothelial activation, dysfunction, and vascular inflammation in adjuvant-induced arthritis (AIA) rats

Fig. 3

Aortic expression of endothelial activation markers at the preclinical stage and at onset of arthritis in AIA rats. mRNA expression of ICAM-1 (A, F), VCAM-1 (B, G), CXCL-1 (C, H), MCP-1 (CCL-2) (D, I), and MIP-1α (CCL-3) (E, J) was studied in thoracic aorta of control and AIA rats at the preclinical stage (day 4 post-immunization, AE) and at the onset of arthritis (day 11 post-immunization, FJ) by qRT-PCR. Results are expressed as means ± SEM (n=number of rats/group). *(p<0.05), ***(p<0.001). NS, non-significant

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