Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis

Table 1 The lectins showed significant altered NFIs in OA models and patients compared with their corresponding controls

Lectin	Specificity	OA models / sham-operated groups				OA patients / normal controls
Lectin	Specificity	0 weeks/ control	4 weeks/ controls	8 weeks/ controls	12 weeks/ controls	OA patients / normal controls
PSA	Fucα-1,6GlcNAc, α-D-Man, α-D-Glc	2.586*	3.272**	2.489**	5.104***	3.585***
AAL	α-Fucose	/	2.261*	2.064*	1.976*	2.322**
WGA	(GlcNAc)_n and multivalent Sia	/	1.791*	2.693*	2.155**	2.309***
LTL	Fucα1-3Galβ1-4GlcNAc, Fucα1-anti-H blood group specificity	/	/	2.339**	3.084**	2.196**
ConA	High-Mannose type N-glycans	/	0.484*	0.408*	0.556*	0.410***

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