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Table 1 The lectins showed significant altered NFIs in OA models and patients compared with their corresponding controls

From: Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis

Lectin Specificity OA models / sham-operated groups OA patients / normal controls
0 weeks/ control 4 weeks/ controls 8 weeks/ controls 12 weeks/ controls
PSA Fucα-1,6GlcNAc, α-D-Man, α-D-Glc 2.586* 3.272** 2.489** 5.104*** 3.585***
AAL α-Fucose / 2.261* 2.064* 1.976* 2.322**
WGA (GlcNAc)n and multivalent Sia / 1.791* 2.693* 2.155** 2.309***
LTL Fucα1-3Galβ1-4GlcNAc, Fucα1-anti-H blood group specificity / / 2.339** 3.084** 2.196**
ConA High-Mannose type N-glycans / 0.484* 0.408* 0.556* 0.410***
  1. / no significant difference, * p < 0.05, ** p < 0.01, and *** p < 0.001