Fig. 2
The effect of ExoBMSC and ExoPTH on OA chondrocyte proliferation was assayed by a flow cytometry, a scratch migration assay, and CCK-8 assay. A Flow cytometry was used to explore the cell proliferation of the OA, ExoBMSC, and ExoPTH groups by the EdU flow cytometry kit. B A scratch wound-healing migration assay was performed with control, OA, ExoBMSC, and ExoPTH treatments. C Statistical results of the scratch wound-healing migration assay. D The cell proliferation ability of the control, OA, ExoBMSC, and ExoPTH groups was detected by a CCK-8 assay. Data are presented as the mean ± SD, *p < 0.05 versus OA group and #p < 0.05 versus ExoBMSC group. Ctrl, control; OA, osteoarthritis; ExoBMSC, exosomes derived from BMSCs; ExoPTH, exosomes derived from PTH-preconditioned BMSCs; BMSCs, bone marrow mesenchymal stem cells