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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: PTH (1-34) enhances the therapeutic effect of bone marrow mesenchymal stem cell-derived exosomes by inhibiting proinflammatory cytokines expression on OA chondrocyte repair in vitro

Fig. 2

The effect of ExoBMSC and ExoPTH on OA chondrocyte proliferation was assayed by a flow cytometry, a scratch migration assay, and CCK-8 assay. A Flow cytometry was used to explore the cell proliferation of the OA, ExoBMSC, and ExoPTH groups by the EdU flow cytometry kit. B A scratch wound-healing migration assay was performed with control, OA, ExoBMSC, and ExoPTH treatments. C Statistical results of the scratch wound-healing migration assay. D The cell proliferation ability of the control, OA, ExoBMSC, and ExoPTH groups was detected by a CCK-8 assay. Data are presented as the mean ± SD, *p < 0.05 versus OA group and #p < 0.05 versus ExoBMSC group. Ctrl, control; OA, osteoarthritis; ExoBMSC, exosomes derived from BMSCs; ExoPTH, exosomes derived from PTH-preconditioned BMSCs; BMSCs, bone marrow mesenchymal stem cells

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Arthritis Research & Therapy

ISSN: 1478-6362

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