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Table 2 Pregnancy outcomes of SSc, APS, SLE patients, and healthy controls

From: Systemic sclerosis and pregnancy outcomes: a retrospective study from a single center

 

SSc (n = 21)

SLE (n = 26)

APS (n = 31)

HC (n = 40)

Total no. of pregnancies

33

40

41

40

Maternal age at delivery (years, mean ± SD)

35.4 ± 4.1

34.6 ± 5.1

35.3 ± 3.7

33.3 ± 5.6

Disease duration at conception (years, mean ± SD)

6.0 ± 5.4

9.4 ± 5.9

2.5 ± 4.4

NA

Gestational age at delivery (weeks, mean ± SD)

31.6 ± 11.7

36.9 ± 8.6

34.1 ± 9.4

39.1 ± 1.8

Adverse pregnancy outcome

20 (60.6)

15 (37.5)a

15 (36.6)b

4 (10)c

Total number of fetal losses

6 (18.18)

4 (10)

6 (16.6)

0

 1st trimester (miscarriage)

5 (15.2)

4 (10)

3 (7.3)

0d

 2nd trimester

0

0

2 (4.9)

0

 3rd trimester

1 (3)

0

1 (2.4)

0

Voluntary and therapeutic abortions

1 (3)

0

0

0

Neonatal deaths

0

0

4 (9.8)

0

IUGR (< 5th percentile)

5 (15.2)

5 (12.5)

5 (12.2)

2 (5)e

Small for gestational age newborns

7 (21.2)

2 (5.0)

8 (19.5)

0 (0)f

Preterm delivery (< 37 weeks of gestation)

8 (24.2)

3 (7.5)g

9 (22)

2 (5)h

Preeclampsia

4 (12.12)

4 (10)

4 (9.8)

0 (0)i

Eclampsia

0

0

0

0

Cesarean delivery

6 (18.2)

9 (22.5)

14 (34.1)

8 (20)

 Elective

4 (12.1)

3 (7.5)

5 (12.2)

8 (20)

 Non-elective

2 (6.1)

6 (15)

9 (21.9)

0 (0)

  1. Values are expressed as numbers (%) of total pregnancies
  2. Abbreviations: SSc systemic sclerosis, SLE systemic lupus erythematosus, APS antiphospholipid syndrome, HC healthy controls, IUGR intrauterine growth restriction
  3. ap = 0.014 SSc compared to SLE
  4. bp = 0.06 SSc compared to APS
  5. cp = 0.001 SSc compared to HC
  6. dp = 0.016 SSc compared to HC
  7. ep = 0.143 SSc compared to HC
  8. fp = 0.003 SSc compared to HC
  9. gp = 0.038 SSc compared to SLE
  10. hp = 0.036 SSc compared to HC
  11. ip = 0.038 SSc compared to HC