From: Systemic sclerosis and pregnancy outcomes: a retrospective study from a single center
SSc (n = 21) | SLE (n = 26) | APS (n = 31) | HC (n = 40) | |
---|---|---|---|---|
Total no. of pregnancies | 33 | 40 | 41 | 40 |
Maternal age at delivery (years, mean ± SD) | 35.4 ± 4.1 | 34.6 ± 5.1 | 35.3 ± 3.7 | 33.3 ± 5.6 |
Disease duration at conception (years, mean ± SD) | 6.0 ± 5.4 | 9.4 ± 5.9 | 2.5 ± 4.4 | NA |
Gestational age at delivery (weeks, mean ± SD) | 31.6 ± 11.7 | 36.9 ± 8.6 | 34.1 ± 9.4 | 39.1 ± 1.8 |
Adverse pregnancy outcome | 20 (60.6) | 15 (37.5)a | 15 (36.6)b | 4 (10)c |
Total number of fetal losses | 6 (18.18) | 4 (10) | 6 (16.6) | 0 |
1st trimester (miscarriage) | 5 (15.2) | 4 (10) | 3 (7.3) | 0d |
2nd trimester | 0 | 0 | 2 (4.9) | 0 |
3rd trimester | 1 (3) | 0 | 1 (2.4) | 0 |
Voluntary and therapeutic abortions | 1 (3) | 0 | 0 | 0 |
Neonatal deaths | 0 | 0 | 4 (9.8) | 0 |
IUGR (< 5th percentile) | 5 (15.2) | 5 (12.5) | 5 (12.2) | 2 (5)e |
Small for gestational age newborns | 7 (21.2) | 2 (5.0) | 8 (19.5) | 0 (0)f |
Preterm delivery (< 37 weeks of gestation) | 8 (24.2) | 3 (7.5)g | 9 (22) | 2 (5)h |
Preeclampsia | 4 (12.12) | 4 (10) | 4 (9.8) | 0 (0)i |
Eclampsia | 0 | 0 | 0 | 0 |
Cesarean delivery | 6 (18.2) | 9 (22.5) | 14 (34.1) | 8 (20) |
Elective | 4 (12.1) | 3 (7.5) | 5 (12.2) | 8 (20) |
Non-elective | 2 (6.1) | 6 (15) | 9 (21.9) | 0 (0) |