Table 2 Multivariable analysis of the differences in lipid profile and angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase serum levels between RA patients and controls

Cholesterol, mg/dl

198 ± 45

203 ± 38

0.12

5 (−2–12), 0.18

14 (6–23), 0.001

Triglycerides, mg/dl

144 ± 68

149 ± 88

0.44

HDL cholesterol, mg/dl

52 ± 15

56 ± 15

0.001

1 (−1–4), 0.29

LDL cholesterol, mg/dl

117 ± 37

117 ± 33

0.96

LDL:HDL cholesterol ratio

2.38 ± 0.89

2.25 ± 0.94

0.10

0.01 (−0.15–0.17), 0.95

Non-HDL cholesterol, mg/dl

146 ± 40

147 ± 38

0.72

Lipoprotein (a), mg/dl

38 (14–101)

33 (11–111)

0.99

Apolipoprotein A1, mg/dl

174 ± 39

170 ± 29

0.12

−9 (−15 to −4), 0.001

−9 (−16 to −3), 0.006

Apolipoprotein B, mg/dl

104 ± 29

107 ± 47

0.38

Apo B:Apo A ratio

0.61 ± 0.18

0.64 ± 0.25

0.097

0.05 (0.01–0.09), 0.008

–

Atherogenic index

4.01 ± 1.12

3.88 ± 1.33

0.22

Angiopoietin-like protein 4, ng/ml

73 (47–121)

151 (90–290)

<0.001

215 (147–284), <0.001

295 (213–376), <0.001

Apolipoprotein C3, mg/dl

6.2 ± 5.6

8.8 ± 5.2

<0.001

2.9 (1.9–3.9), <0.001

2.9 (1.7–4.0), <0.001

Lipoprotein lipase, ng/ml

230 (183–328)

99 (60–156)

<0.001

−121 (−160 to −82), <0.001

−174 (−213 to −135), <0.001