Table 3 Disease-related data relation with angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase axis

Disease duration, years

−7 (−14–0), 0.058

0.04 (−0.04–0.12), 0.32

4 (0–7), 0.025

CRP, mg/l

1 (−3–5), 0.67

0.05 (0.01–0.10), 0.013

1 (−1–3), 0.46

ESR, mm/1st hour

−3 (−6 to −1), 0.020

−0.00 (−0.03–0.03), 0.93

1 (0–3), 0.033

Rheumatoid factor

18 (−116–153), 0.79

0.2 (−1.2–1.6), 0.77

35 (−28–99), 0.27

ACPA

117 (−12–247), 0.075

0.2 (−1.2–1.5), 0.80

61 (−5–128), 0.068

DAS28-ESR

−19 (−93–16), 0.17

−0.4 (−1.0–0.2), 0.18

7 (−18–32), 0.58

DAS28-PCR

−15 (−75–45), 0.63

−0.4 (−1.0–0.3), 0.25

2 (−26–30), 0.88

SDAI

0 (−3–4), 0.88

0.03 (−0.01–0.06), 0.17

0 (−1–2), 0.70

CDAI

−2 (−10–6), 0.66

−0.08 (−0.16–0.01), 0.069

0 (−3–4), 0.90

HAQ

−25 (−128–77), 0.62

−0.3 (−1.4–0.8), 0.60

52 (9–94), 0.017

Current drugs

 Prednisone

22 (−105–149), 0.73

−0.1 (−1.4–1.3), 0.94

−10 (−69–49), 0.74

 Prednisone, mg/day

16 (−28–59), 0.47

−0.2 (−0.5–0.1), 0.15

1 (−6–7), 0.87

 NSAIDs

21 (−101–144), 0.73

−0.4 (−1.7–0.8), 0.50

9 (−48–66), 0.77

 DMARDs

−20 (−181–140), 0.80

−0.4 (−2.1–1.3), 0.63

29 (−53–110), 0.49

 Methotrexate

25 (−105–155), 0.71

0.4 (−0.9–1.8), 0.53

41 (−24–106), 0.21

 Leflunomide

−50 (−218–118), 0.56

0.4 (−1.4–2.2), 0.67

51 (−17–119), 0.14

 Hydroxychloroquine

257 (−229–744), 0.30

−3.5 (−8.7–1.6), 0.18

116 (30–202), 0.008

 Salazopyrin

150 (−819–1120), 0.76

−3.6 (−13.9–6.6), 0.49

143 (41–245), 0.006

 Anti-TNF therapy

−11 (−182–159), 0.90

−0.2 (−2.1–1.6), 0.79

101 (33–169), 0.004

 Tocilizumab

53 (−204–311), 0.68

−1.3 (−4.0–1.4), 0.35

9 (−118–137), 0.89

 Rituximab

−202 (−601–197), 0.32

0.0 (−4.3–4.2), 0.99

−23 (−228–181), 0.82

 Abatacept

−182 (−581–217), 0.37

3.9 (−0.3–8.1), 0.069

−58 (−263–146), 0.58

 JAK inhibitors

347 (−22–715), 0.065

−3.6 (−7.5–0.3), 0.072

−39 (−216–139), 0.67

History of extraarticular manifestations

−136 (−349–76), 0.21

0.4 (−1.9–2.7), 0.76

37 (−54–127), 0.42

Erosions

17 (−122–157), 0.81

−1.0 (−2.4–0.4), 0.16

57 (−7–121), 0.081