Diagnostic procedure | Parameter | Cutoff | Sensitivity | Specificity | LR+ | LR− |
---|---|---|---|---|---|---|
Combination of PFT and chest X-ray | DLCO and/or chest X-ray | < 80% | 95.2% | 38.7% | 1.55 | 0.12 |
< 70% | 88.7% | 64.5% | 2.50 | 0.18 | ||
TLC and/or chest X-ray | < 80% | 69.4% | 73.8% | 2.65 | 0.41 | |
< 70% | 64.5% | 77.0% | 2.80 | 0.46 | ||
TLCO and/or chest X-ray | < 80% | 78.7% | 58.1% | 1.88 | 0.37 | |
< 70% | 68.9% | 69.4% | 2.25 | 0.45 | ||
FVC and/or chest X-ray | < 80% | 80.6% | 66.1% | 2.38 | 0.29 | |
< 70% | 71.0% | 74.2% | 2.75 | 0.39 | ||
FEV1 and/or chest X-ray | < 80% | 80.6% | 66.1% | 2.38 | 0.29 | |
< 70% | 71.0% | 74.2% | 2.75 | 0.39 | ||
Combination of PFT and HRCT | DLCO and HRCT | < 80% | 83.6% | 83.1% | 4.95 | 0.20 |
< 70% | 67.2% | 88.1% | 5.65 | 0.37 | ||
TLC and HRCT | < 80% | 32.1% | 98.2% | 17.83 | 0.69 | |
< 70% | 23.2% | 100.0% | > 100 | 0.77 | ||
TLCO and HRCT | < 80% | 57.6% | 81.4% | 3.10 | 0.52 | |
< 70% | 32.2% | 91.5% | 3.79 | 0.74 | ||
FVC and HRCT | < 80% | 47.5% | 93.4% | 7.20 | 0.56 | |
< 70% | 32.2% | 95.1% | 6.57 | 0.71 | ||
FEV1 and HRCT | < 80% | 50.8% | 93.4% | 7.70 | 0.53 | |
< 70% | 33.9% | 95.1% | 6.92 | 0.70 | ||
Combination of the following: 1. PFT and chest X-ray 2. HRCT | 1. DLCO and/or chest X-ray 2. HRCT | < 80% | 95.2% | 77.4% | 4.21 | 0.06 |