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Table 1 Clinical characteristic of TAK patients with or without aortic valve involvement

From: Risk factors and surgical prognosis in patients with aortic valve involvement caused by Takayasu arteritis

Variable Total (n=172) Aortic valve involvement (n=92) Non-aortic valve involvement (n=80) P
Age at symptom onset, years 28.00 (23.00, 38.00) 30.00 (23.00, 41.75) 26.50 (20.00, 36.00) 0.030
Duration of disease, months 48.00 (12.00, 144.00) 60.00 (12.00,165.00) 36.00 (8.25, 120.00) 0.160
Female, n (%) 147 (85.5) 81 (88.0) 66 (82.5) 0.304
History, n (%)
 Smoking 21 (12.2) 6 (6.5) 15 (18.8) 0.015
 Hypertension 52 (30.2) 28 (30.4) 24 (30.0) 0.951
 Hyperlipidemia 17 (9.9) 9 (9.8) 8 (10.0) 0.962
 Diabetes mellitus 8 (4.7) 2(2.2) 6 (7.5) 0.197
 Coronary artery disease 15 (8.7) 11 (12.0) 4 (5.0) 0.107
 Medication 59 (34.3) 36 (39.1) 23 (28.7) 0.153
  Glucocorticoid 53 (31.5) 32 (36.4) 21 (26.3) 0.159
  Immunosuppressant 42 (25.0) 23 (26.1) 19 (23.8) 0.721
Clinical symptoms, n (%)
 Chest tightness 58 (33.7) 41 (44.6) 17 (21.3) 0.001
 Chest pain 34 (19.8) 21 (22.8) 13 (16.3) 0.280
 Palpitation 24 (14.0) 16 (17.4) 8 (10.0) 0.163
 Shortness of breath 19 (11.0) 17 (18.5) 2 (2.5) 0.001
 Hemoptysis 5 (2.9) 2 (2.2) 3 (3.8) 0.874
 Dizziness 71 (41.3) 39 (42.4) 32 (40.0) 0.751
 Amaurosis 6 (3.5) 4 (4.3) 2 (2.5) 0.809
 Consciousness 8 (4.7) 3 (3.3) 5 (6.3) 0.572
 Fever 21 (12.2) 13 (14.1) 8 (10.0) 0.409
 Fatigue 72 (41.9) 38 (41.3) 34 (42.5) 0.874
 Headache 27 (15.7) 12 (13.0) 15 (18.8) 0.305
 Carotidynia 20 (11.6) 8 (8.7) 12 (15.0) 0.198
 Limb pain 19 (11.0) 12 (13.0) 7 (8.8) 0.370
 Intermittent claudication 27 (15.7) 9 (9.8) 18 (22.5) 0.022
 Weak pulse or pulselessness 39 (22.7) 21 (22.8) 18 (22.5) 0.959
 Upper limb blood pressure asymmetry 53 (30.8) 25 (27.2) 28 (35.0) 0.268
Typea, n (%)
 I 23 (15.8) 7 (10.4) 16 (20.3) 0.105
 IIa 7 (4.8) 5 (7.5) 2 (2.5) 0.317
 IIb 22 (15.1) 16 (23.9) 6 (7.6) 0.006
 III 7 (4.8) 1 (1.5) 6 (7.6) 0.183
 IV 4 (2.7) 0 (0) 4 (5.1) 0.174
 V 83 (56.8) 38 (56.7) 45 (57.0) 0.976
 C 35 (24.0) 21 (31.3) 14 (17.7) 0.055
 P 26 (17.8) 15 (22.4) 11 (13.9) 0.183
  1. aType is defined according to the distribution of the involved artery; Type is divided according to Hata and Numano’s criteria; C, indicates any lesion with coronary artery involvement; P, indicates any lesion with pulmonary artery involvement