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Table 4 Determinants of GAVE on multivariate analysis

From: Gastric antral vascular ectasia in systemic sclerosis: a study of its epidemiology, disease characteristics and impact on survival

Variable

Odds Ratio (95% CI)

p-value

a) Determinants of GAVE

 Age at SSc onseta, years

1.01 (1.00-1.02)

0.092

 Diffuse disease subtype

1.48 (1.06-2.06)

0.023

 GIT dysmotility

1.57 (1.15-2.14)

0.005

 SSc renal crisis

2.10 (1.12-3.91)

0.020

 DU, pits or amputation

1.46 (1.02-2.07)

0.036

b) Determinants of GAVE by autoantibody status

 Age at SSc onseta, years

1.01 (1.00-1.03)

0.015

 ANA centromere positivity

1.28 (0.88-1.86)

0.204

 Scl-70 positivity

0.26 (0.11-0.62)

0.002

 RNAP III positivity

3.92 (2.50-6.16)

<0.001

 GIT dysmotility

1.66 (1.19-2.32)

0.003

 DU, pits or amputation

1.59 (1.10-2.30)

0.014

  1. Abbreviations: SSc systemic sclerosis, GAVE gastric antral vascular ectasia, GIT gastrointestinal tract, DU, Scl-70 antitopoisomerase-1, RNAP anti RNA Polymerase III, CI confidence interval
  2. aage defined as from first non-Raynaud’s disease manifestation