From: Apolipoprotein C-III in patients with systemic lupus erythematosus
SLE patients | |
---|---|
(n = 186) | |
Age, years | 50 ± 11 |
Women, n (%) | 177 (95) |
Body mass index, kg/m2 | 27 ± 5 |
Abdominal circumference, cm | 92 ± 13 |
Systolic blood pressure, mmHg | 128 ± 20 |
Diastolic blood pressure, mmHg | 84 ± 52 |
Cardiovascular comorbidity | |
Smoking, n (%) | 31 (17) |
Diabetes, n (%) | 0 (0) |
Hypertension, n (%) | 70 (28) |
Obesity, n (%) | 48 (26) |
Statins, n (%) | 45 (24) |
Aspirin, n (%) | 48 (26) |
Antihypertensive treatment, n (%) | 65 (35) |
Analytical and lipid profile data | |
CRP, mg/dl | 1.9 (0.9–4.9) |
Cholesterol, mg/dl | 200 ± 38 |
Triglycerides, mg/dl | 127 ± 81 |
HDL cholesterol, mg/dl | 63 ± 21 |
LDL cholesterol, mg/dl | 111 ± 29 |
LDL:HDL cholesterol ratio | 1.92 ± 0.74 |
Non-HDL cholesterol, mg/dl | 198 ± 38 |
Apolipoprotein A1, mg/dl | 179 ± 37 |
Apolipoprotein B, mg/dl | 96 ± 23 |
Apo B:A1 ratio | 0.55 ± 0.16 |
Lipoprotein (a), mg/dl | 37 (13–106) |
Atherogenic index | 3.4 ± 1.1 |
Apolipoprotein C3, mg/dl | 1.75 (1.24–2.59) |
SLE-related data | |
Disease duration, years | 17 ± 9 |
SLICC | 1 (0–2) |
SLICC ≥ 1, n (%) | 136 (73) |
Katz index | 2 (1–3) |
SLEDAI | 2 (0–5) |
SLEDAI categories, n (%) | |
No activity, n (%) | 73 (39) |
Mild or moderate, n (%) | 90 (48) |
High or very high, n (%) | 13 (7) |
Auto-antibody profile | |
Anti-DNA positive, n (%) | 96 (52) |
ENA positive, n (%) | 63 (34) |
Anti-Ro, n (%) | 61 (33) |
Anti-La, n (%) | 30 (16) |
Anti-RNP, n (%) | 47 (25) |
Anti-Sm, n (%) | 21 (11) |
Any antiphospholipid autoantibodies, n (%) | |
Lupus anticoagulant, n (%) | 36 (19) |
ACA IgM, n (%) | 20 (11) |
ACA IgG, n (%) | 30 (16) |
Anti-beta2 glycoprotein IgM, n (%) | 12 (6) |
Anti-beta2 glycoprotein IgG, n (%) | 22 (12) |
C3, mg/dl | 143 ± 52 |
C4, mg/dl | 27 ± 14 |
Current prednisone, n (%) | 95 (51) |
Prednisone, mg/day | 5 (5–7.5) |
DMARDs, n (%) | 144 (77) |
Hydroxychloroquine, n (%) | 126 (68) |
Hydroxychloroquine, mg/day | 200 (200–300) |
Methotrexate, n (%) | 21 (11) |
Mycophenolate mofetil, n (%) | 15 (8) |
Azathioprine, n (%) | 25 (13) |
Rituximab, n (%) | 6 (3) |
Belimumab, n (%) | 3 (2) |