Skip to main content

Table 3 Multivariable analysis of the relationship of SLE activity, severity, and damage scores with apolipoprotein C3

From: Apolipoprotein C-III in patients with systemic lupus erythematosus

 

SLICC

Katz index

SLEDAI

Beta coef. (95% CI), p

Lipid profile

  Cholesterol, mg/dl

0.3 (− 2–3), 0.84

 − 0.06 (− 3–3), 0.97

1 (0–2), 0.17

  Triglycerides, mg/dl

2 (− 4–8), 0.59

 − 1 (− 7–6), 0.83

 − 1 (− 3–2), 0.63

  HDL cholesterol, mg/dl

0.1 (− 1–2), 0.88

1 (0–3), 0.12

1 (0–1), 0.11

  LDL cholesterol, mg/dl

 − 0.2 (− 2–2), 0.89

 − 1 (− 3–1), 0.30

0.4 (0–1), 0.36

  LDL:HDL cholesterol ratio

0.02 (− 0.4–0.07), 0.50

 − 0.05 (− 0.11–0.01), 0.080

 − 0.005 (− 0.03–0.02), 0.67

  Non-HDL cholesterol, mg/dl

0.3 (− 2–3), 0.85

0.01 (− 3–3), 0.99

1 (0–2), 0.16

  Apolipoprotein A1, mg/dl

1 (− 2–3), 0.66

2 (− 1–5), 0.25

1 (0–2), 0.068

  Apolipoprotein B, mg/dl

 − 1 (− 2–1), 0.48

 − 0.2 (− 2–2), 0.82

0.2 (− 1–1), 0.59

  Apo B: A1 ratio

 − 0.004 (− 0.2–0.01), 0.49

 − 0.01 (− 0.02–0.00), 0.22

0.0009 (− 0.01–0.00), 0.73

  Lipoprotein (a), mg/dl

 − 3 (− 9–4), 0.41

0.5 (-6–7), 0.89

1 (− 2–3), 0.67

  Atherogenic index

0.04 (− 0.04–0.12), 0.38

 − 0.06 (− 0.14–0.02), 0.16

 − 0.01 (− 0.04–0.02), 0.48

Apolipoprotein C3, mg/dl

  Unadjusted

0.14 (0.06–0.23), 0.001

0.10 (0.01–0.19), 0.030

0.02 (− 0.01–0.06), 0.19

  Adjusted #1

0.10 (0.02–0.19), 0.020

0.10 (0.02–0.19), 0.015

0.04 (0.00–0.07), 0.036

  Adjusted #2

 

0.11 (0.03–0.19), 0.011*

0.05 (0.02–0.08), 0.004**

  1. Beta coefficients represent the relation of SLICC, Katz, and SLEDAI score (independent variable) to each of the lipid profile molecules including ApoC3 (dependent variables). Significant p values are depicted in bold
  2. LDL low-density lipoprotein, HDL high-density lipoprotein, SLEDAI Systemic Lupus Erythematosus Disease Activity Index, SLICC Systemic Lupus International Collaborating Clinics/American Colleague of Rheumatology Damage Index
  3. #1 adjusted for age, BMI, systolic blood pressure, and statins
  4. #2 adjusted for age, BMI, systolic blood pressure, and statins, plus any lipid profile molecule that has a univariable relation with the score inferior to 0.20
  5. *Adjusted for age, BMI, systolic blood pressure, and statins + HDL cholesterol; **adjusted for age, BMI, systolic blood pressure, and statins + cholesterol, HDL cholesterol, and apolipoprotein A1
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us