Fig. 2

Increased frequency of IgD-CD27^hiCD38^hi B cells in patients with active AAV. A The frequency of IgD-CD27^hiCD38^hi B cells among CD19+ B cells was significantly increased in the AAV patients in active stage than those in both AAV patients in remission and healthy donors. B The frequency of IgD-CD27^hiCD38^hi B cells among CD45+ leukocytes was significantly increased in the AAV patients in active stage than those in both AAV patients in remission and healthy donors. C The frequency of IgD-CD27^hiCD38^hi B cells among CD19+ B cells was significantly increased in active stage than that in remission in 8 AAV patients with sequential blood samples of both active stage and remission. D The frequency of IgD-CD27^hiCD38^hi B cells among CD45+ leukocytes was significantly increased in active stage than that in remission in 8 AAV patients with sequential blood samples of both active stage and remission