Table 1 Clinical and histopathologic data of patients with active AAV
General clinical data | Number (%) |
|---|---|
Number | 26 |
Male/female | 15/11 |
Age (years) | 61.1 ± 12.3 |
MPO-ANCA/PR3-ANCA | 23/3 |
The duration between symptomatic disease and diagnosis (months) | |
 Median | 3.0 |
 Range | 0.5–45.0 |
Scr (μmol/L) | |
 Mean ± SD | 481.8 ± 246.9 |
 Range | 106.7–955.0 |
eGFR (ml/min/1.73m2) | |
 Mean ± SD | 14.6 ± 10.7 |
 Range | 4.4–47.6 |
Urinary protein (g/24 h) | |
 Median | 0.71 |
 Range | 0.11–8.31 |
BVAS | 17.4 ± 4.8 |
Renal pathological data | |
Number | 14 |
Normal glomeruli (%) | 35.6 ± 20.9 |
Glomerular lesions (%) | |
 Total crescents | 59.2 ± 23.6 |
 Cellular crescents | 52.9 ± 21.5 |
 Fibrous crescents | 6.3 ± 12.3 |
 Fibrinoid necrosis | 3.2 ± 3.1 |
 Global sclerosis | 2.0 ± 3.4 |
Tubulointerstitial lesions | |
 Interstitial infiltration (−/+/++/+++) | 0/2/10/2 |
 Interstitial fibrosis (−/+/++) | 1/2/11 |
 Tubular atrophy (−/+/++) | 1/10/3 |