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Table 2 Association of clinical parameter and imaging parameter (inflammatory parameter in the area of Achilles tendon) assessed with categories improvement/no improvement from screening to week 24

From: Magnetic resonance imaging characteristics in patients with spondyloarthritis and clinical diagnosis of heel enthesitis: post hoc analysis from the phase 3 ACHILLES trial

Parameter

Achilles tendon enthesitis

Heel pain

Heel enthesopathy

Intra-tendon hypersignal

P=0.496 (n=83)

P=0.903 (n=74)

P=0.724 (n=74)

Peri-tendon hypersignal

P=0.335 (n=68)

P=0.773 (n=58)

P=0.003 (n=58)

Bursitis

P=0.092 (n=72)

P=0.021 (n=61)

P=0.095 (n=61)

BME

P=0.057 (n=54)

P=0.303 (n=46)

P=0.268 (n=46)

  1. Achilles tendon enthesitis, single tender point out of the 6-point LEI (binary assessment 0,1); heel pain, 0–10 NRS reported by patients; heel enthesopathy, 0–100 VAS reported by patients; Associations calculated based on chi-square test with categories improvement/no-improvement (parameters that remained stable from screening to Week 24 were considered as “no-improvement”); all subjects with respective HEMRIS parameter present at screening were considered for the analysis
  2. BME Bone marrow edema, HEMRIS  Heel Enthesitis Magnetic Resonance Imaging Scoring system, LEI Leeds Enthesitis Index, NRS Numeric rating scale, VAS Visual analog scale
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Arthritis Research & Therapy

ISSN: 1478-6362

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