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Table 1 Baseline demographics of treatment-naïve RA patients recruited into the Pathobiology of Early Arthritis Cohort (PEAC)

From: Network analysis of synovial RNA sequencing identifies gene-gene interactions predictive of response in rheumatoid arthritis

 

Lympho-myeloid (N = 49)

Diffuse myeloid (N = 18)

Pauci immune fibroid (N = 16)

Total (N = 83)

p-value

Age (years)

52.3 (16.2)

50.4 (16.5)

53.2 (15.0)

52.1 (15.9)

0.865

Gender

    

0.608

 F

37 (75.5%)

12 (66.7%)

13 (81.2%)

62 (74.7%)

 

 M

12 (24.5%)

6 (33.3%)

3 (18.8%)

21 (25.3%)

 

Disease duration (months)

5.9 (3.3)

4.8 (2.6)

7.0 (3.5)

5.8 (3.3)

0.152

RF

    

0.203

 pos

32 (69.6%)

9 (52.9%)

7 (46.7%)

48 (61.5%)

 

 neg

14 (30.4%)

8 (47.1%)

8 (53.3%)

30 (38.5%)

 

CCP

    

0.025

 pos

39 (84.8%)

10 (55.6%)

9 (60.0%)

58 (73.4%)

 

 neg

7 (15.2%)

8 (44.4%)

6 (40.0%)

21 (26.6%)

 

DAS28

6.2 (1.2)

5.6 (1.2)

5.2 (1.6)

5.8 (1.3)

0.029

ESR (mm/hr)

50.9 (28.1)

37.6 (25.4)

30.8 (27.7)

44.1 (28.4)

0.025

CRP (μg/mL)

25.0 (26.5)

17.5 (26.0)

14.4 (41.7)

21.3 (29.9)

0.395

TJC

12.6 (7.2)

9.9 (6.3)

10.9 (8.9)

11.7 (7.4)

0.396

SJC

8.4 (5.7)

7.1 (4.3)

5.2 (5.0)

7.5 (5.4)

0.116

VAS

67.9 (24.0)

61.1 (21.7)

57.8 (27.1)

64.5 (24.2)

0.287

HAQ

1.6 (0.8)

1.4 (0.6)

1.6 (0.8)

1.5 (0.7)

0.499

DAS28 EULAR

    

0.603

 Good

15 (36.6%)

4 (30.8%)

7 (53.8%)

26 (38.8%)

 

 Moderate

20 (48.8%)

8 (61.5%)

4 (30.8%)

32 (47.8%)

 

 None

6 (14.6%)

1 (7.7%)

2 (15.4%)

9 (13.4%)

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