HCs n=80 | pSS n=142 | P | |
---|---|---|---|
Sex (female/male), n | 64/16 | 124/18 | 0.146 |
Age (years), mean ± SD | 55.91±7.17 | 57.90±8.94 | 0.090 |
Numbers of lymphocytes (cells/μl), median(range) | |||
T cells | 1205.25 (646.00, 2415.00) | 1175.10 (137.26, 3309.97) | 0.340 |
B cells | 177.41 (52.93, 406.00) | 213.17 (12.34, 861.13) | 0.135 |
CD4+T cells | 655.00 (299.11, 1513.00) | 627.74 (28.42, 1902.81) | 0.430 |
CD8+T cells | 414.54 (103.00, 1084.48) | 445.43 (42.26, 1779.72) | 0.925 |
NK cells | 260.50 (52.00, 896.04) | 164.00 (13.00, 1107.52) | <0.001 |
Th1 cells | 105.37 (2.69, 515.96) | 88.83 (2.14, 1224.46) | 0.247 |
Th2 cells | 8.27 (0.96, 27.04) | 7.41 (0.28, 71.03) | 0.402 |
Th17 cells | 6.44 (0.82, 18.18) | 5.24 (0.22, 64.90) | 0.264 |
Treg cells | 33.36 (13.26, 70.96) | 27.71 (0.14, 139.28) | 0.002 |
Proportions of lymphocytes (%), median (range) | |||
T cells | 72.00 (50.00, 84.72) | 71.95 (43.39, 92.87) | 0.847 |
B cells | 10.60 (4.65, 23.00) | 14.00 (1.76, 46.00) | 0.001 |
CD4+T cells | 39.82 (22.86, 57.26) | 39.09 (10.23, 59.26) | 0.675 |
CD8+T cells | 24.10 (6.00, 48.45) | 25.00 (8.73, 62.70) | 0.443 |
NK cells | 15.04 (3.00, 31.00) | 10.34 (1.00, 39.23) | <0.001 |
Th1 cells | 16.25 (0.25, 49.7) | 15.05 (0.32, 83.23) | 0.517 |
Th2 cells | 1.22 (0.18, 3.93) | 1.08 (0.26, 12.06) | 0.773 |
Th17 cells | 0.92 (0.16, 2.78) | 0.93 (0.20, 11.02) | 0.689 |
Treg cells | 5.13 (2.06, 8.28) | 4.26 (1, 18.99) | <0.001 |
CD4+T/CD8+T | 1.64 (0.48, 6.38) | 1.48 (0.22, 6.14) | 0.335 |
Th1/Th2 | 12.93 (0.62, 204) | 12.06 (0.15, 121.42) | 0.921 |
Th17/Treg | 0.17 (0.03, 0.79) | 0.21 (0.02, 2.06) | 0.217 |