Table 2 HRs (95% CIs) for incident myocardial infarction and all-cause mortality per trajectory of SUA trajectories

 Cases, n (%)

342 (0.78)

372 (1.08)

103 (1.48)

<0.0001

 Incidence rate^a

1.18 (1.07–1.32)

1.66 (1.50–1.84)

2.29 (1.89–2.77)

 Model 1

Reference

1.41 (1.21–1.63)

1.94 (1.56–2.42)

<0.0001

 Model 2

Reference

1.14 (0.98–1.32)

1.53 (1.22–1.91)

<0.0001

 Model 3

Reference

1.10 (0.95–1.28)

1.35 (1.07–1.71)

0.0146

 Sensitivity analysis^b

Reference

1.09 (0.93–1.27)

1.33 (1.05–1.67)

0.0264

 Sensitivity analysis^c

Reference

1.06 (0.88–1.28)

1.50 (1.14–1.97)

0.0158

 Sensitivity analysis^d

Reference

1.06 (0.91–1.23)

1.33 (1.06–1.66)

0.0317

 Sensitivity analysis^e

Reference

1.10 (0.94–1.28)

1.33 (1.05–1.68)

0.0246

 Cases, n (%)

2886 (6.54)

2884 (8.38)

728 (10.48)

<0.0001

 Incidence rate

9.96 (9.61–10.30)

12.80 (12.40–13.30)

16.10 (14.90–17.30)

 Model 1

Reference

1.29 (1.23–1.36)

1.63 (1.50–1.76)

<0.0001

 Model 2

Reference

1.00 (0.95–1.05)

1.18 (1.09–1.28)

0.0040

 Model 3

Reference

1.04 (0.98–1.10)

1.22 (1.12–1.33)

<0.0001

 Sensitivity analysis^b

Reference

1.04 (0.99–1.10)

1.20 (1.10–1.30)

<0.0001

 Sensitivity analysis^c

Reference

1.04 (0.98–1.11)

1.24 (1.12–1.38)

0.0003

 Sensitivity analysis^d

Reference

1.02 (0.94–1.05)

1.15 (1.06–1.26)

0.0022

 Sensitivity analysis^f

Reference

1.03 (0.97–1.10)

1.21 (1.10–1.34)

0.0010