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Table 3 Changes in organ damage before and after the introduction of the MPZ group and the IVCY group

From: Safety and effectiveness of mepolizumab therapy in remission induction therapy for eosinophilic granulomatosis with polyangiitis: a retrospective study

 

MPZ group

IVCY group

0 M

1 M

3 M

6 M

0 M

1 M

3 M

6 M

General symptoms

6 (85.7%)

0

0

0

11 (91.7%)

0

0

0

Cutaneous manifestations

5 (71.4%)

1 (14.3%)

0

0

8 (66.7%)

4 (33.3%)

1 (8.3%)

0

ENT manifestations

5 (71.4%)

1 (14.3%)

1 (14.3%)

1 (14.3%)

7 (58.3%)

6 (50.0%)

2 (16.7%)

2 (16.7%)

Heart manifestations

1 (14.3%)

1 (14.3%)

0

0

2 (16.7%)

0

0

0

Chest manifestations

5 (71.4%)

3 (42.9%)

1 (14.3%)

0

7 (58.3%)

3 (25.0%)

1 (8.3%)

1 (8.3%)

Abdominal manifestations

1 (14.3%)

0

0

0

0

0

0

0

Renal manifestations

2 (28.6%)

0

0

0

2 (16.7%)

1 (8.3%)

0

0

Sensor nervous system manifestations

5 (71.4%)

5 (71.4%)

5 (71.4%)

5 (71.4%)

11 (91.7%)

11 (91.7%)

11 (91.7%)

11 (91.7%)

Motor nervous system manifestations

2 (28.6%)

2 (28.6%)

2 (28.6%)

2 (28.6%)

6 (46.2%)

6 (46.2%)

6 (46.2%)

6 (46.2%)

  1. ENT ear, nose, throat; MPZ mepolizumab; IVCY intravenous cyclophosphamide