Table 1 Distribution of characteristics of patients with rheumatoid arthritis by cohort and data source
Cohort 1 | Cohort 2 | Cohort 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|
SSDI N = 135,886 | Marketscan N = 202,906 | SMD | SSDI N = 119,516 | Marketscan N = 186,441 | SMD | SSDI N = 39,972 | Marketscan N = 49,686 | SMD | |
Age in years, mean (SD) | 54.8 (6.5) | 53.4 (6.7) | 0.20 | 54.7 (6.5) | 53.4 (6.7) | 0.21 | 54.3 (6.5) | 53.1 (6.6) | 0.20 |
Age,% | 0.20 | 0.20 | 0.19 | ||||||
40–44 | 8.8 | 12.6 | 8.8 | 12.8 | 9.4 | 13.0 | |||
45–49 | 14.0 | 17.2 | 14.1 | 17.5 | 15.5 | 17.9 | |||
50–54 | 21.3 | 22.6 | 21.4 | 22.6 | 22.2 | 24.0 | |||
55–59 | 26.7 | 25.0 | 26.7 | 24.8 | 26.4 | 25.3 | |||
60–64 | 29.2 | 22.7 | 29.0 | 22.3 | 26.5 | 19.8 | |||
Male, % | 21.9 | 23.9 | 0.05 | 21.3 | 23.6 | 0.06 | 16.9 | 20.9 | 0.10 |
Diabetes, % | 31.9 | 15.4 | 0.40 | 31.5 | 15.1 | 0.40 | 38.2 | 19.5 | 0.42 |
Hypertension, % | 61.6 | 38.5 | 0.48 | 61.0 | 37.8 | 0.48 | 68.8 | 46.1 | 0.47 |
High risk CVD, % | 21.1 | 8.2 | 0.37 | 20.4 | 7.9 | 0.37 | 24.8 | 10.3 | 0.39 |
Obesity, % | 7.0 | 2.7 | 0.20 | 6.9 | 2.7 | 0.20 | 9.2 | 4.6 | 0.18 |
Smoking, % | 20.4 | 4.4 | 0.50 | 20.0 | 4.2 | 0.50 | 22.5 | 5.0 | 0.53 |
CKD, % | 5.8 | 1.6 | 0.23 | 5.3 | 1.5 | 0.21 | 5.0 | 1.7 | 0.18 |
Glucocorticoids, % | 59.6 | 53.5 | 0.12 | 62.3 | 56.4 | 0.12 | 73.4 | 72.5 | 0.03 |
csDMARD, % | 69.8 | 66.0 | 0.08 | 78.7 | 66.0 | 0.29 | 90.5 | 89.9 | 0.02 |
bDMARD, % | 29.6 | 27.7 | 0.04 | 33.9 | 30.6 | 0.07 | 52.5 | 46.5 | 0.12 |
tsDMARD, % | 0.5 | 0.4 | 0.01 | 0.5 | 0.4 | 0.01 | 1.9 | 2.2 | 0.01 |
NSAIDS, % | 56.1 | 55.6 | 0.01 | 56.8 | 57.0 | 0.00 | 57.8 | 58.0 | 0.00 |
Statin, % | 31.2 | 21.8 | 0.21 | 31.5 | 22.3 | 0.21 | 31.7 | 22.1 | 0.22 |
Hospitalizations, % | 22.9 | 9.6 | 0.37 | 21.8 | 9.2 | 0.36 | 22.4 | 10.9 | 0.31 |
Number of physician visit, mean (SD) | 16.1 (10.7) | 11.3 (7.2) | 0.53 | 15.9 (10.6) | 11.1 (7.2) | 0.54 | 17.9 (11.1) | 13.6 (7.8) | 0.45 |