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Table 1 Distribution of characteristics of patients with rheumatoid arthritis by cohort and data source

From: Comparing cardiovascular risk of patients with rheumatoid arthritis within the Social Security Disability Insurance with those commercially insured

  Cohort 1 Cohort 2 Cohort 3
  SSDI
N = 135,886
Marketscan
N = 202,906
SMD SSDI
N = 119,516
Marketscan
N = 186,441
SMD SSDI
N = 39,972
Marketscan
N = 49,686
SMD
Age in years, mean (SD) 54.8 (6.5) 53.4 (6.7) 0.20 54.7 (6.5) 53.4 (6.7) 0.21 54.3 (6.5) 53.1 (6.6) 0.20
Age,%    0.20    0.20    0.19
40–44 8.8 12.6   8.8 12.8   9.4 13.0  
45–49 14.0 17.2   14.1 17.5   15.5 17.9  
50–54 21.3 22.6   21.4 22.6   22.2 24.0  
55–59 26.7 25.0   26.7 24.8   26.4 25.3  
60–64 29.2 22.7   29.0 22.3   26.5 19.8  
Male, % 21.9 23.9 0.05 21.3 23.6 0.06 16.9 20.9 0.10
Diabetes, % 31.9 15.4 0.40 31.5 15.1 0.40 38.2 19.5 0.42
Hypertension, % 61.6 38.5 0.48 61.0 37.8 0.48 68.8 46.1 0.47
High risk CVD, % 21.1 8.2 0.37 20.4 7.9 0.37 24.8 10.3 0.39
Obesity, % 7.0 2.7 0.20 6.9 2.7 0.20 9.2 4.6 0.18
Smoking, % 20.4 4.4 0.50 20.0 4.2 0.50 22.5 5.0 0.53
CKD, % 5.8 1.6 0.23 5.3 1.5 0.21 5.0 1.7 0.18
Glucocorticoids, % 59.6 53.5 0.12 62.3 56.4 0.12 73.4 72.5 0.03
csDMARD, % 69.8 66.0 0.08 78.7 66.0 0.29 90.5 89.9 0.02
bDMARD, % 29.6 27.7 0.04 33.9 30.6 0.07 52.5 46.5 0.12
tsDMARD, % 0.5 0.4 0.01 0.5 0.4 0.01 1.9 2.2 0.01
NSAIDS, % 56.1 55.6 0.01 56.8 57.0 0.00 57.8 58.0 0.00
Statin, % 31.2 21.8 0.21 31.5 22.3 0.21 31.7 22.1 0.22
Hospitalizations, % 22.9 9.6 0.37 21.8 9.2 0.36 22.4 10.9 0.31
Number of physician visit, mean (SD) 16.1 (10.7) 11.3 (7.2) 0.53 15.9 (10.6) 11.1 (7.2) 0.54 17.9 (11.1) 13.6 (7.8) 0.45
  1. SSDI Social Security Disability Insurance
  2. Cohort: 1 = two diagnosis code for rheumatoid arthritis (RA), at least 1 from rheumatologist; 2 = one diagnosis code for RA followed by use of disease-modifying antirheumatic drugs (DMARDS, biologic or small molecule); 3 = cohort 2 plus initiation of a biologic or tofacitinib
  3. CKD chronic kidney disease, SMD standardized mean difference, Other CVD other cardiovascular disease defined as coronary artery disease including angina pectoris, peripheral artery disease or atherosclerosis, transient ischemic attack, heart failure, atrial fibrillation, aortic aneurysm or dissection, and nontraumatic intracranial hemorrhage (not leading to stroke)