Skip to main content

Table 3 Matrix prediction model. Probability of achieving a good response to methotrexate at 24 weeks

From: Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data

  

HQA

  

 ≤ 2

 > 2

DAS28-ESR

 ≤ 7.4

80.1 (76.4, 83.8)

77.3 (70.6, 84)

Positive

ACPA status

77.1 (68.6, 85.6)

74.1 (63.3, 84.9)

Negative

 > 7.4

40.3 (32.1, 48.5)

36.5 (29.3, 43.6)

Positive

36.2 (23.3, 49.1)

32.5 (20.9, 44.1)

Negative

  1. The number in each cell represents the percentage and 95% CI of achieving the outcome, based on the combination of predictors at baseline. DAS28-ESR, Disease Activity Score with 28-joint count with erythrocyte sedimentation rate, HAQ, Health Assessment Questionnaire; ACPA, anti-citrullinated protein antibody