Table 2 Immunological characteristics of the cryoglobulin in SLE patients
From: Cryoglobulinemia in systemic lupus erythematosus: a retrospective study of 213 patients
SLE CG+ (n = 142) | |
|---|---|
Type I cryoglobulinemia, n (%) | 1 (1%) |
Type II cryoglobulinemia, n (%) | 27 (19%) |
Type III cryoglobulinemia, n (%) | 114 (80%) |
Ig concentration in cryoprecipitate (mg/L) | |
Total, mean (range) | 40 (0-228) |
IgG, mean (range) | 21 (0-107) |
IgA, mean (range) | 1 (0-27) |
IgM, mean (range) | 19 (0-228) |
Type I cryoglobulinemia | |
Monoclonal IgMκ, n (%) | 1 (1%) |
Type II cryoglobulinemia isotypes | |
Monoclonal IgMκ + polyclonal IgG/IgM, n (%) | 15 (11%) |
Monoclonal IgGκ + polyclonal IgG/IgM, n (%) | 4 (3%) |
Monoclonal IgMλ + polyclonal IgG/IgM, n (%) | 4 (3%) |
Monoclonal IgGλ + polyclonal IgG/IgM, n (%) | 2 (1%) |
Type III cryoglobulinemia isotypes | |
Polyclonal IgG + polyclonal IgM, n (%) | 73 (51%) |
Polyclonal IgG, n (%) | 22 (15%) |
Polyclonal IgG + polyclonal IgM + polyclonal IgA, n (%) | 3 (2%) |
Polyclonal IgM, n (%) | 1 (1%) |
RF activity | |
Negative RF in cryoprecipitate, n (%) | 125 (88%) |
Positive RF in cryoprecipitate, n (%) | 3 (2%) |