Table 3 SLE laboratory features in SLE patients according to the presence of a cryoglobulin
From: Cryoglobulinemia in systemic lupus erythematosus: a retrospective study of 213 patients
SLE CG+ (n = 142) | SLE CG− (n = 71) | p value | |
|---|---|---|---|
Immunology | |||
RF in serum positive, n (%) | 6 (4%) | 5 (7%) | 0.51 |
RF in serum, UI/L, mean (± SD) | 119 ± 100 | 107 ± 110 | 0.69 |
Hypogammaglobulinemia, n (%) | 6 (4%) | 3 (4%) | 1.00 |
Hypergammaglobulinemia, n (%) | 87 (61%) | 34 (48%) | 0.06 |
Gammaglobulins, g/L, mean (± SD) | 16.2 ± 6.0 | 16.8 ± 7.0 | 0.89 |
Decreased complement C3, n (%) | 96 (68%) | 32 (45%) | 0.002 |
Decreased complement C4, n (%) | 107 (75%) | 33 (46%) | <0.00013 |
Decreased CH50, n (%) | 91 (64%) | 28 (39%) | 0.0006 |
Farr test, UI/L, mean (± SD) | 72.2 ± 88.0 | 42.7 ± 51.2 | 0.07 |
Anti-SSA antibodies, n (%) | 72 (51%) | 32 (45%) | 0.44 |
Anti-Sm antibodies, n (%) | 55 (39%) | 22 (31%) | 0.27 |
Anti-RNP antibodies, n (%) | 65 (46%) | 27 (38%) | 0.28 |
Infections | |||
HBV infection, n (%) | 2 (1%) | 0 (0%) | 0.90 |
HIV infection, n (%) | 0 (0%) | 0 (0%) | 1.00 |
Cytopenia | |||
Leukopenia, n (%) | 36 (25%) | 22 (31%) | 0.38 |
Lymphopenia, n (%) | 89 (63%) | 40 (56%) | 0.37 |
Thrombopenia, n (%) | 36 (25%) | 18 (25%) | 1.00 |
Autoimmune hemolytic anemia, n (%) | 23 (16%) | 9 (13%) | 0.50 |