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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Transcriptome analysis of immune cells from Behçet’s syndrome patients: the importance of IL-17-producing cells and antigen-presenting cells in the pathogenesis of Behçet’s syndrome

Fig. 4

A memory CD8+ T cell module with IL-17-associated genes shows a correlation with HLA-B51 positivity. A An enlarged view of modules showing correlation with HLA-B51 positivity in BS patients. B Tc17 score in HLA-B51-positive patients (n = 7) compared to HLA-B51-negative patients (n = 17). C Pathway analysis of “MCD8_08,” the module with the strongest positive correlation with HLA-B51 positivity. Pathways with absolute z scores 2 are shown. D Pathway analysis of “NCD8_06,” the module with the strongest negative correlation with HLA-B51 positivity. Pathways with absolute z scores 5 are shown

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