Fig. 2From: Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degenerationKnockdown of Bmal1 led to the degeneration of NP cells in vitro. a The mRNA levels of Bmal1 in the control and si-Bmal1 groups. b The mRNA levels of Acan and Mmp13 in the control and si-Bmal1 groups. n = 3, *P<0.05, **P < 0.01. c–f Immunofluorescence staining images and quantification of Aggrecan and MMP13 in the control and si-Bmal1 groups (scale bar: 25 μm). n = 3, **P < 0.01Back to article page