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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration

Fig. 3

Si-Bmal1 decreased the expression of NRF2 and increased the ROS, inflammatory response, and apoptosis. a, b Immunofluorescence staining images and quantification of NRF2 in the control and si-Bmal1 groups (scale bar: 25 μm). n = 3, **P < 0.01. c, d DCFDA staining images and quantification in the control and si-Bmal1 groups. n = 3, **P < 0.01. e The mRNA levels of Il-1β, Tnf-α, and Il-6 in the control and si-Bmal1 groups. n = 3, *P<0.05, **P < 0.01. f, g TUNEL staining and quantification in the control and si-Bmal1 groups (scale bar: 25 μm). n = 3, **P < 0.01

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